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Plga Poly Lactic Glycolic Acid. It is the best defined biomaterial available for drug delivery with respect to design and performance. PLGA poly lactic co glycolic acid 1. PLGA containing lactic and glycolic acids is a commercial polymer approved by the United States Food and Drug Administration FDA for its biocompatibility biodegradability nontoxicity and excellent mechanical properties 1 2 28. The device performance was analyzed in terms of the volume fraction of PLGA in the active layer blend as well as with respect to three different lacticglycolic monomer ratios 8515 7525 6535.
Specifically PLGA materials are also developed for the dental field in the form of scaffolds films membranes microparticles or nanoparticles. PolyDL-lactic acid-co-glycolic acid is a copolymer composed of 2-hydroxypropanoyl and 2-hydroxyacetyl units. Poly DL- lactide- co- glycolide acid. Patel Institute of Pharmaceutical Education and Research Shirpur Maharashtra India. Polylactic-co-glycolic acid PLGA is commonly used as an in situ pore forming agent in CPC and the morphology of PLGA would affect the properties of CPC. Among various polymers polylactic-co-glycolic acid PLGA has received the highest attention because of its favorable degradation characteristics and biocompatibility.
Poly lactic-co-glycolic acid PLGA is widely used in biomedical fields as bone fixation materials sutures materials drug delivery and tissue engineering applications because of its tailorable degradation rates biocompatibility and formability 15 17.
PLGA is biocompatible and biodegradable exhibits a wide range of erosion times has tunable mechanical properties and most importantly is a FDA approved polymer. PolyDL-lactic-co-glycolic acid PLGA is the most frequently used biodegradable polymer in the controlled release of encapsulated drugs. PLGA is biocompatible and biodegradable exhibits a wide range of erosion times has tunable mechanical properties and most importantly is a FDA approved polymer. Polyester PLGA is a copolymer of poly lactic acid PLA and poly glycolic acid PGA. Among various polymers polylactic-co-glycolic acid PLGA has received the highest attention because of its favorable degradation characteristics and biocompatibility. The most commonly used biodegradable synthetic polymers for three-dimensional 3D scaffolds in tissue engineering are saturated polyα-hydroxy esters including polylactic acid PLA and polyglycolic acid PGA as well as polylactic-co-glycolide PLGA copolymers 1112.