Methylprednisolone Spinal Cord Injury. Its use in acute SCI has been the subject of controversy for over 30 years. Consensus statements consider methylprednisolone as a treatment option for acute spinal cord injury. High-dose methylprednisolone treatment when given within 8 hours of spinal cord injury results in significant improvements in motor recovery compared with placebo. Comment on J Neurosurg.
Clinical Trials as Topic. METHYLPREDNISOLONE IN ACUTE SPINAL CORD INJURY SUMMARY The administration of methylprednisolone MP for patients with acute spinal cord injury ASCI has been highly controversial. Consensus statements consider methylprednisolone as a treatment option for acute spinal cord injury. Steroids for acute spinal cord injury. Comment on J Neurosurg. Segatore M Way C.
MP can confer neuroprotective effects to patients by mitigating the secondary response to ASCI.
Methylprednisolone for spinal cord injury. Comment on J Neurosurg. Keywords methylprednisolone sodium succinate MPSS spinal cord injury systematic review traumatic spinal cord injury. Moreover the use of MP is associated with an increased risk of infectious and metabolic complications during ICU stay. However there are significant risks associated with MP administration. METHYLPREDNISOLONE IN ACUTE SPINAL CORD INJURY SUMMARY The administration of methylprednisolone MP for patients with acute spinal cord injury ASCI has been highly controversial.