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Jul
H5n1 And H1n1 Difference. Unlike the avian H5N1 flu the H1N1 swine flu is capable of being transmitted easily from person to person. H1N1 flu is caused by a new virus that is different from the seasonal flu we usually see each fall and winter. However few DEGs were detected and various cellular functions and signaling pathways were dramatically suppressed in the H5N1 group. Comparing influenza to coronavirus is more like comparing dogs and cats.
In contrast in well differentiated cultures H5N1 virus replication was less efficient and elicited a lower interferon-beta response in comparison with H1N1 virus. Our data suggest that the differentiation of bronchial. Human infections are primarily acquired through direct contact with infected animals or contaminated environments these. The 2009 H1N1 influenza pandemic has also been much less severe than the H5N1 pandemic scenario that drove pandemic planning for the past 5 years. In perhaps the most important difference between the two pandemics of the 21st century H1N1 illnesses responded well to anti-viral drugs already used to treat the flu. When compared to H1N1 virus the H5N1 virus replicated more efficiently and induced a stronger type I interferon response in the undifferentiated NHBE cells.
When this confounding variable is considered in our statistical model a clear set of dysregulated genes and pathways emerges specifically in H5N1 virus-infected macrophages at 6-h post infection whilst was not found with H1N1 virus infection.
Since then costly control measures have been introduced including culling of infected birds and vaccination of poultry 1. There are differences between the viruses that make them more or less contagious for people more or less easily passed from animals to people and more or less severe and deadly. With an in-depth study on the H1N1. There are many H and N subtypes and each one is numbered. Compared with any two of the three IAV-infected groups many more differentially expressed genes DEGs cellular functions and signaling pathways were confirmed in H1N1 or H7N2 group with the H7N2 group showing the highest levels. The new H7N9 strain emerging in China does not make birds ill for instance but has been killing about a third of infected humans.