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Anti Beta 2 Gp1 Igg. Beta 2 glycoprotein-I beta 2 GPI is a 50 kDa plasma protein which associates with a number of anionic plasma constituents and has been identified as a cofactor for the binding of some antiphospholipid antibodies aPAs. Anticorps anti-bêta 2 glycoprotéine 1 - B2GP1 - IgG - sérum Liste des examens. Beta 2 glycoprotein IgG is a type of antibody found in the blood. In contrast in the group of 18 sera lacking anti-beta 2GP1 antibodies ACA were largely restricted to IgG3 with a lesser contribution by IgG1.
Persistent positivity increased the association of IgG anti-beta2-GPI with venous thrombosis and anti-beta2-GPI IgM with arterial thrombosis. Beta-2 GP1 antibodies are found with increased frequency in patients with systemic rheumatic diseases especially systemic lupus erythematosus. Strongly positive results for beta 2 glycoprotein 1 beta 2 GP1 antibodies 40 UmL for IgG andor IgM are diagnostic criterion for antiphospholipid syndrome APS. Beta 2 glycoprotein IgG is a type of antibody found in the blood. B2GPI results greater than 20 SGU IgG andor SMU IgM are considered positive based on the cutoff values established for this test. Prezenţa unuia sau ambelor tipuri de anticorpi constituie un factor de risc independent.
Lesser levels of IgG and IgM beta 2 GP1 antibodies and antibodies of the IgA isotype may occur in patients with clinical signs of APS but the results are not considered diagnostic.
Beta-2 glycoprotein 1 antibody is a protein c-factro that binds to phospholipids. Lesser levels of IgG and IgM beta 2 GP1 antibodies and antibodies of the IgA isotype may occur in patients with clinical signs of APS but the results are not considered diagnostic. Phospholipids are lipid-proteins found in the outermost layer of cells cell membrane including blood cells such as platelets. Il kit Anti beta 2 Glycoprotein 1 IgG è destinato al solo uso di laboratorio. Reference values apply to all ages. Persistence is defined as moderate or high levels of IgG andor IgM B2GPI antibodies detected in two or more specimens drawn at least 12 weeks apart J Throm Haemost.